We examined the effects of vitamin B12 injections, combined with folic acid, on 38 patients with myalgic encephalomyelitis (ME), also known as chronic fatigue syndrome.
Participants were split into "Good" and "Mild" responders based on their improvement. Good responders reported greater progress with more frequent injections and higher doses of both supplements.
However, for Mild responders, the improvement was limited, suggesting that while there is potential for benefit, the response can vary widely among individuals. Overall, further investigation is needed to explore optimal treatment strategies.
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Most Useful Reviews
2
Sleeplessness issue
27 people found this helpful
I took the first capsule in the morning and couldn’t sleep at all, not even the following night. While the vitamins helped with my brain fatigue, the resulting sleeplessness negated the benefits. There may be a stimulant in it; I’d caution anyone with sleep issues about this supplement.
Read More
9
Energy boost
8 people found this helpful
This vitamin B complex, with its active form, has energised me quickly. Unlike regular multivitamins, it significantly alleviated my fatigue and I highly recommend it for those dealing with chronic fatigue syndrome.
Read More
9
Brain fog relief
8 people found this helpful
For over a decade, chronic fatigue syndrome and brain fog affected my life. I bought this product on a whim, and it has tremendously improved my energy. I'm thrilled to feel like my old self again.
We examined the effects of vitamin B12 injections, combined with folic acid, on 38 patients with myalgic encephalomyelitis (ME), also known as chronic fatigue syndrome.
Participants were split into "Good" and "Mild" responders based on their improvement. Good responders reported greater progress with more frequent injections and higher doses of both supplements.
However, for Mild responders, the improvement was limited, suggesting that while there is potential for benefit, the response can vary widely among individuals. Overall, further investigation is needed to explore optimal treatment strategies.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 49 Reviews
7.2
All Reviews
Positive Reviews
Negative Reviews
2
Sleeplessness issue
27 people found this helpful
I took the first capsule in the morning and couldn’t sleep at all, not even the following night. While the vitamins helped with my brain fatigue, the resulting sleeplessness negated the benefits. There may be a stimulant in it; I’d caution anyone with sleep issues about this supplement.
Read More
9
Energy boost
8 people found this helpful
This vitamin B complex, with its active form, has energised me quickly. Unlike regular multivitamins, it significantly alleviated my fatigue and I highly recommend it for those dealing with chronic fatigue syndrome.
Read More
9
Brain fog relief
8 people found this helpful
For over a decade, chronic fatigue syndrome and brain fog affected my life. I bought this product on a whim, and it has tremendously improved my energy. I'm thrilled to feel like my old self again.
Read More
9
Increased energy levels
2 people found this helpful
Recommended to me for chronic fatigue syndrome, I was sceptical but gave it a try. Within a week, my energy levels improved remarkably. I believe this formulation is highly bioavailable, helping significantly with my fatigue-related symptoms.
Read More
9
Life-changing vitamin
2 people found this helpful
After years of chronic fatigue syndrome, this vitamin has made a huge difference in my life. It alleviated my fatigue and helped with insomnia. My husband also noticed the positive effects. It's certainly a product I’ll keep buying.
Chronic Fatigue Syndrome (CFS), also known as Myalgic Encephalomyelitis (ME), is a complex and debilitating condition characterized by profound fatigue that doesn’t improve with rest and worsens with physical or mental activity. This crippling fatigue is often accompanied by a variety of symptoms, including sleep disturbances, cognitive difficulties, muscle pain, and joint pain. Unlike typical tiredness, the fatigue experienced in CFS is long-lasting, and it can significantly hinder everyday activities and overall quality of life.
The precise cause of CFS remains unknown, but it is believed to be influenced by a combination of genetic, environmental, immunological, and psychological factors. Diagnosis primarily relies on a careful assessment of symptoms, as there are no definitive laboratory tests available. Treatment options focus on symptom management and may include lifestyle changes, physical therapy, medication for pain management, and cognitive behavioral therapy. Given the complexity and variability of the condition, individuals with CFS should consult healthcare professionals who specialize in this area to develop personalized management strategies.
Vitamin B Complex refers to a group of water-soluble vitamins that play important roles in cell metabolism and overall health. This group typically includes eight essential vitamins: B1 (thiamine), B2 (riboflavin), B3 (niacin), B5 (pantothenic acid), B6 (pyridoxine), B7 (biotin), B9 (folate), and B12 (cobalamin). Each of these vitamins contributes uniquely to various bodily functions, such as energy production, red blood cell formation, and nervous system function. For instance, B12 and folate are crucial in preventing anemia, while B6 is vital for brain development and function.
Many people can obtain their daily requirements of B vitamins through a balanced diet that includes whole grains, meats, eggs, nuts, leafy greens, and dairy products. However, certain groups—like vegetarians, pregnant women, and older adults—may benefit from supplementation to meet their nutritional needs. It's important to consult with a healthcare professional before starting any supplement regimen, as excessive intake of certain B vitamins can lead to adverse effects. Overall, ensuring adequate intake of Vitamin B Complex is vital for maintaining energy levels and supporting overall health.
While there is no definitive cure for Chronic Fatigue Syndrome (CFS), some research suggests that Vitamin B Complex may play a supportive role in managing symptoms. The B vitamins, including B1, B2, B3, B5, B6, B7, B9, and B12, are essential for energy production and metabolic processes in the body. Many individuals with CFS report low energy levels and fatigue, which can be exacerbated by deficiencies in these vitamins. Supplementing with a B Complex may help improve energy levels, cognitive function, and overall well-being for some, although results can vary from person to person.
It's important to note that while B vitamins may be beneficial, they should not be viewed as a substitute for a comprehensive treatment plan. Consulting with a healthcare professional is crucial for personalized advice and proper diagnosis. Should you decide to try a Vitamin B Complex, look for high-quality products that include the full range of B vitamins and consider discussing with your doctor for tailored recommendations that complement any existing treatment strategies.
Based on user reviews, many individuals taking this supplement for Chronic Fatigue Syndrome have reported noticing improvements in their energy levels within a week of use. For instance, one user mentioned experiencing significant energy improvements just seven days after starting the supplement Read Review. Another customer shared that after one week, their energy was noticeably better, highlighting the product's effectiveness in combating fatigue Read Review.
However, experiences can vary widely; while some users felt revitalized quickly, others emphasized the need for patience, as results may not be immediate for everyone. Overall, the general consensus suggests that many users see benefits within a week or two, underscoring the importance of regular use for the best results. Still, it's advisable to consult with a healthcare provider to tailor any supplementation to individual health needs and situations.
The use of vitamin B12 and folic acid for Chronic Fatigue Syndrome (CFS) is supported by some scientific research, particularly a study that evaluated their effects on 38 patients diagnosed with myalgic encephalomyelitis (ME), which falls under the umbrella of CFS. The findings indicated that while some patients, categorized as "Good" responders, experienced significant improvements with higher doses and more frequent injections, others, termed "Mild" responders, showed limited benefits. This variability suggests that individual responses can differ considerably, highlighting the need for more comprehensive research to identify optimal treatment strategies [1].
While these results are promising, they also emphasize that vitamin B12 and folic acid may not be a one-size-fits-all solution for those suffering from CFS. The evidence suggests some potential benefits, but it's clear that further testing is required to fully understand the implications of these supplements in CFS management. If you're considering this combination, it's advisable to consult with a healthcare professional who can tailor treatments to your specific condition and needs.
Based on user reviews, many individuals taking this vitamin B complex supplement for Chronic Fatigue Syndrome report marked improvements in their symptoms. Users have mentioned feeling revitalized, with one individual citing a significant reduction in fatigue after just a week of use Read Review. Another reviewer shared that they were able to reclaim their energy and feel like their old self again after suffering from fatigue and brain fog for over a decade Read Review, while others appreciate the product's ability to enhance overall well-being and energy levels Read Review.
However, it's important to note that individual results can vary significantly. While many users report improvements, some have also experienced adverse effects such as insomnia or skin rashes, requiring them to stop taking the supplement Read ReviewRead Review. Despite these mixed experiences, the overall sentiment leans towards the efficacy of the supplement in alleviating fatigue associated with chronic fatigue syndrome when used as directed. Always consider discussing with a healthcare provider before starting any new supplement regimen.
Based on user reviews, many individuals have shared positive experiences when combining this vitamin B complex supplement with other supplements while managing Chronic Fatigue Syndrome. Users report enhanced energy levels and improved symptoms, particularly when used alongside a routine that includes other supportive nutrients. One reviewer noted that the product's advanced formulation, which promotes effective absorption, made a significant difference in their energy and overall well-being Read Review. Additionally, another user mentioned integrating it into their regimen during menopause to combat fatigue, highlighting versatility in its application Read Review.
However, users also caution against potential adverse effects when taken with other supplements. For instance, one user experienced insomnia, which they attributed to possible stimulant effects of the B vitamins, advising those with sleep issues to be cautious Read Review. Similarly, another individual faced adverse reactions, including skin rashes, which prompted them to stop use Read Review. It seems that while many users find success with combinations, individual responses can vary greatly, underscoring the importance of consulting a healthcare provider to ensure safe and effective supplementation.
Users report varied experiences regarding the right dose of Vitamin B Complex for treating Chronic Fatigue Syndrome (CFS). Many users, such as those in reviews Read Review and Read Review, highlight effective improvements in energy levels with the use of this supplement. However, there are concerns about potential side effects related to dosage; for instance, a user noted significant fatigue and concentration issues, attributing it to a potentially high vitamin dose Read Review.
Additionally, some users experienced irritability or sleep disturbances, suggesting that higher doses might not be suitable for everyone Read Review. Overall, while many users advocate for vitamin B as an energizing remedy for CFS, they recommend monitoring individual reactions and possibly adjusting the dosage accordingly, with some suggesting that smaller capsule versions might reduce waste and enhance efficacy Read Review.
9
Increased energy levels
2 people found this helpful
Recommended to me for chronic fatigue syndrome, I was sceptical but gave it a try. Within a week, my energy levels improved remarkably. I believe this formulation is highly bioavailable, helping significantly with my fatigue-related symptoms.
9
Increased energy
1 people found this helpful
It works perfectly! After a week of use, I've regained my energy due to chronic fatigue syndrome. As a nursing mother, I need all the energy I can get, and these tablets are easy to swallow. I definitely recommend them!
9
Brain fog relief
8 people found this helpful
For over a decade, chronic fatigue syndrome and brain fog affected my life. I bought this product on a whim, and it has tremendously improved my energy. I'm thrilled to feel like my old self again.
9
Steady energy
1 people found this helpful
Doctor's Best Fully Active B Complex has been a valuable ally in my battle against chronic fatigue syndrome. Its advanced formulation ensures effective vitamin absorption and offers sustained energy release, enhancing my overall well-being. The vegetarian capsules align well with my dietary choices, and I appreciate its commitment to quality.
2
Sleeplessness issue
27 people found this helpful
I took the first capsule in the morning and couldn’t sleep at all, not even the following night. While the vitamins helped with my brain fatigue, the resulting sleeplessness negated the benefits. There may be a stimulant in it; I’d caution anyone with sleep issues about this supplement.
7.5
Skin rash
1 people found this helpful
Initially, this product reduced my fatigue significantly, but by the third day, I developed a dreadful skin rash, so I had to stop taking it.
6
Reduced menopausal fatigue
1 people found this helpful
Taking vitamin B every few days has helped with chronic fatigue syndrome, especially during menopause. The capsules are small and easy to take, improving my overall energy levels.
9
Energy boost
8 people found this helpful
This vitamin B complex, with its active form, has energised me quickly. Unlike regular multivitamins, it significantly alleviated my fatigue and I highly recommend it for those dealing with chronic fatigue syndrome.
0
No concentration
I felt fatigued and unable to concentrate after taking this. I hadn’t experienced such problems with another brand of vitamin B complex. I believe the dosage of vitamins included is too high.
7.5
Capsule recommendation
2 people found this helpful
I found the vitamin B complex effective for chronic fatigue syndrome, but I suggest buying the 30-capsule version instead of 60. The 60 capsules discoloured quickly, leading to waste, despite being cheaper.
7
B12 and folic acid show variability
Response to vitamin B12 and folic acid in myalgic encephalomyelitis and fibromyalgia.
We examined the effects of vitamin B12 injections, combined with folic acid, on 38 patients with myalgic encephalomyelitis (ME), also known as chronic fatigue syndrome.
Participants were split into "Good" and "Mild" responders based on their improvement. Good responders reported greater progress with more frequent injections and higher doses of both supplements.
However, for Mild responders, the improvement was limited, suggesting that while there is potential for benefit, the response can vary widely among individuals. Overall, further investigation is needed to explore optimal treatment strategies.
References
Regland B, Forsmark S, Halaouate L, Matousek M, Peilot B, et al. Response to vitamin B12 and folic acid in myalgic encephalomyelitis and fibromyalgia. PLoS One. 2015;10:e0124648. doi:10.1371/journal.pone.0124648