Overview

SCIENTIFIC SCORE
Possibly Effective
Based on 1 Research
7
USERS' SCORE
Moderately Good
Based on 49 Reviews
7.2
Supplement Facts
Serving Size:  1 Veggie Capsule
Amount Per Serving
%DV
Vitamin C (as ascorbic acid)
40 mg
44%
Thiamin (as thiamin HCl)
60 mg
5000%
Riboflavin (as riboflavin and riboflavin-5-phosphate)
75 mg
5769%
Niacin (as niacinamide and niacin)
50 mg
313%
Vitamin B6 (from pyridoxine HCl and pyridoxal-5-phosphate)
50 mg
2941%
Folate (as (6S)-5-methyltetrahydrofolic acid, glucosamine salt) (Quatrefolic®)
400 mcg DFE
100%
Vitamin B12 (as methylcobalamin)
1000 mcg
41677%
Biotin
600 mcg
2000%
Pantothenic Acid (as d-calcium pantothenate)
100 mg
2000%

Top Medical Research Studies

We examined the effects of vitamin B12 injections, combined with folic acid, on 38 patients with myalgic encephalomyelitis (ME), also known as chronic fatigue syndrome.

Participants were split into "Good" and "Mild" responders based on their improvement. Good responders reported greater progress with more frequent injections and higher doses of both supplements.

However, for Mild responders, the improvement was limited, suggesting that while there is potential for benefit, the response can vary widely among individuals. Overall, further investigation is needed to explore optimal treatment strategies.
Read More

Most Useful Reviews

2
Sleeplessness issue
27 people found this helpful
I took the first capsule in the morning and couldn’t sleep at all, not even the following night. While the vitamins helped with my brain fatigue, the resulting sleeplessness negated the benefits. There may be a stimulant in it; I’d caution anyone with sleep issues about this supplement.
Read More
9
Energy boost
8 people found this helpful
This vitamin B complex, with its active form, has energised me quickly. Unlike regular multivitamins, it significantly alleviated my fatigue and I highly recommend it for those dealing with chronic fatigue syndrome.
Read More
9
Brain fog relief
8 people found this helpful
For over a decade, chronic fatigue syndrome and brain fog affected my life. I bought this product on a whim, and it has tremendously improved my energy. I'm thrilled to feel like my old self again.
Read More

Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 1 Research
7
  • All Researches
We examined the effects of vitamin B12 injections, combined with folic acid, on 38 patients with myalgic encephalomyelitis (ME), also known as chronic fatigue syndrome.

Participants were split into "Good" and "Mild" responders based on their improvement. Good responders reported greater progress with more frequent injections and higher doses of both supplements.

However, for Mild responders, the improvement was limited, suggesting that while there is potential for benefit, the response can vary widely among individuals. Overall, further investigation is needed to explore optimal treatment strategies.
Read More

User Reviews

USERS' SCORE
Moderately Good
Based on 49 Reviews
7.2
  • All Reviews
  • Positive Reviews
  • Negative Reviews
2
Sleeplessness issue
27 people found this helpful
I took the first capsule in the morning and couldn’t sleep at all, not even the following night. While the vitamins helped with my brain fatigue, the resulting sleeplessness negated the benefits. There may be a stimulant in it; I’d caution anyone with sleep issues about this supplement.
Read More
9
Energy boost
8 people found this helpful
This vitamin B complex, with its active form, has energised me quickly. Unlike regular multivitamins, it significantly alleviated my fatigue and I highly recommend it for those dealing with chronic fatigue syndrome.
Read More
9
Brain fog relief
8 people found this helpful
For over a decade, chronic fatigue syndrome and brain fog affected my life. I bought this product on a whim, and it has tremendously improved my energy. I'm thrilled to feel like my old self again.
Read More
9
Increased energy levels
2 people found this helpful
Recommended to me for chronic fatigue syndrome, I was sceptical but gave it a try. Within a week, my energy levels improved remarkably. I believe this formulation is highly bioavailable, helping significantly with my fatigue-related symptoms.
Read More
9
Life-changing vitamin
2 people found this helpful
After years of chronic fatigue syndrome, this vitamin has made a huge difference in my life. It alleviated my fatigue and helped with insomnia. My husband also noticed the positive effects. It's certainly a product I’ll keep buying.
Read More

Frequently Asked Questions

9
Increased energy levels
2 people found this helpful
Recommended to me for chronic fatigue syndrome, I was sceptical but gave it a try. Within a week, my energy levels improved remarkably. I believe this formulation is highly bioavailable, helping significantly with my fatigue-related symptoms.
9
Increased energy
1 people found this helpful
It works perfectly! After a week of use, I've regained my energy due to chronic fatigue syndrome. As a nursing mother, I need all the energy I can get, and these tablets are easy to swallow. I definitely recommend them!
9
Brain fog relief
8 people found this helpful
For over a decade, chronic fatigue syndrome and brain fog affected my life. I bought this product on a whim, and it has tremendously improved my energy. I'm thrilled to feel like my old self again.
9
Steady energy
1 people found this helpful
Doctor's Best Fully Active B Complex has been a valuable ally in my battle against chronic fatigue syndrome. Its advanced formulation ensures effective vitamin absorption and offers sustained energy release, enhancing my overall well-being. The vegetarian capsules align well with my dietary choices, and I appreciate its commitment to quality.
2
Sleeplessness issue
27 people found this helpful
I took the first capsule in the morning and couldn’t sleep at all, not even the following night. While the vitamins helped with my brain fatigue, the resulting sleeplessness negated the benefits. There may be a stimulant in it; I’d caution anyone with sleep issues about this supplement.
7.5
Skin rash
1 people found this helpful
Initially, this product reduced my fatigue significantly, but by the third day, I developed a dreadful skin rash, so I had to stop taking it.
6
Reduced menopausal fatigue
1 people found this helpful
Taking vitamin B every few days has helped with chronic fatigue syndrome, especially during menopause. The capsules are small and easy to take, improving my overall energy levels.
9
Energy boost
8 people found this helpful
This vitamin B complex, with its active form, has energised me quickly. Unlike regular multivitamins, it significantly alleviated my fatigue and I highly recommend it for those dealing with chronic fatigue syndrome.
0
No concentration
I felt fatigued and unable to concentrate after taking this. I hadn’t experienced such problems with another brand of vitamin B complex. I believe the dosage of vitamins included is too high.
7.5
Capsule recommendation
2 people found this helpful
I found the vitamin B complex effective for chronic fatigue syndrome, but I suggest buying the 30-capsule version instead of 60. The 60 capsules discoloured quickly, leading to waste, despite being cheaper.
We examined the effects of vitamin B12 injections, combined with folic acid, on 38 patients with myalgic encephalomyelitis (ME), also known as chronic fatigue syndrome.

Participants were split into "Good" and "Mild" responders based on their improvement. Good responders reported greater progress with more frequent injections and higher doses of both supplements.

However, for Mild responders, the improvement was limited, suggesting that while there is potential for benefit, the response can vary widely among individuals. Overall, further investigation is needed to explore optimal treatment strategies.

References

  1. Regland B, Forsmark S, Halaouate L, Matousek M, Peilot B, et al. Response to vitamin B12 and folic acid in myalgic encephalomyelitis and fibromyalgia. PLoS One. 2015;10:e0124648. doi:10.1371/journal.pone.0124648
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